With more than 30 years of experience in manufacturing natural SAMe (S-adenosylmethionine) by fermentation and several patents for related stabilized salts, Gnosis is the worldwide leading producer of SAMe for pharmaceutical, nutritional and veterinary markets.

Adonat® –SAMe is a naturally occurring compound present in all living cell where sustains their normal function. It is an important intermediate in one-carbon metabolism and acts as methyl donor in more than one hundred biochemical pathways and specific processes.

• Adonat –SAMe is required for the synthesis of neurotrasmitters such as norepinephrine, dopamine and serotonin, the lack of which are thought to be involved in the development of mood disorders and other brain impairments.

• Adonat –SAMe supplementation could both ameliorate liver injury and helps to restore normal hepatic function.

• Adonat –SAMe helps supporting the incorporation of sulfate groups into proteoglycans which help to maintain cartilage and protect joints.

• Adonat –SAMe helps the prevention of aging and supports cell and organ longevity

Available as high quality bulk powder, enteric coated tablets and stabilized oral dosage forms, the novel convenient and attractive delivery forms Adonat –SAMe shows:

Adonat® is offered in worldwide markets, for pharmaceutical, nutraceutical, and veterinary applications with peerless quality profile.
• Highest potency of SAMe ion and highest content of the biological active form, the (S,S) active diastereoisomer >75%. (S,S) may degrade rapidly and passively converts in the inactive (R,S) form, which results in the loss of activity of the product
• The longest available shelf-life in the market: 36 months at RT
• GMP Manufacturing, FDA Inspected
• Kosher KOF-K Certified and Halal Certified
• DMF availability
• US, European, Japanese Patents