Kyowa L-Citrulline

Kyowa L-Citrulline – an amino acid that is a better precursor of Arginine and nitric oxide (NO) that support blood circulation.

Citrulline is a non-essential amino acid that promotes vascular dilation which improves oxygen and blood circulation throughout your body. Citrulline is converted to L-arginine in the body, leading to increased production of nitric oxide (NO) and effects such as vasodilation. It is expected to relieve muscle fatigue through promotion of energy production and ammonia elimination. Antioxidant action and heart protection action are also known.

Citrulline is a better precursor of Arginine and nitric oxide (NO) than Arginine itself. This is shown by acute oral administration of Citrulline raising plasma Arginine levels to about 227% with 3.8 grams of Citrulline (within 4 hours) compared to only 90% with the equivalent dose of Arginine. Unlike Arginine, oral Citrulline is readily absorbed without any gastrointestinal side effects. Another benefit includes Citrulline’s ability to recycle Arginine enhancing the duration of the effects and further increasing NO synthesis. Major benefits of Citrulline administration include:

  • Vasodilatation (via NO synthesis)
  • Improves endothelial dysfunction
  • Restore nitrogen balance
  • Increase muscle protein content & muscle protein synthesis
  • Decrease Leukocyte migration
  • Antioxidant