Osteol™: Natural Joint health booster
If not controlled, the inflammatory process can cause huge damage to joints and surrounding tissue. The inflammatory markers increase the synthesis and activity of metalloproteases (MMPs*) and they induce chondrocytes death and cartilage degeneration. Nexira offer Osteol™, a natural joint health booster made from bio-active milk proteins.
Combined with D-Glucosamine & Chondroitin, Osteol offers a powerful booster effect to reduce inflammatory markers (TNF-α) and their harmful effects.
In vitro study showed that the addition of Osteol™ to D-Glucosamine + Chondroitin helps to increase the protection of chondrocytes (cartilage cells) from 25% to 95%. Furthermore, in vitro test on gene expression showed that Osteol combined with D-Glucosamine and Chondroitin helps to protect cartilage from degeneration by:
- Reducing MMPs synthesis
- Stimulating the synthesis of MMPs inhibitor (TIMP3)
The synergistic effect of Osteol combined with D-Glucosamine + Chondroitin allows a reduction of active dosage while strengthening efficiency:
- Stronger reduction of the arthritic index(1) with anactive dosage divided by 2
- Optimized synergistic effect obtained with a specificratio Osteol™/D-Gluco = 1
Osteol™ is clinically tested. It helped to significantly reduce the feeling of pain by nearly 50% on volunteers with nascent osteoarthritis.