New Brunswick, NJ – Natreon’s Crominex®3+ (Trivalent chromium polyphenolic complex) has been granted GRAS approval. GRAS approval demonstrates Natreon’s superiority in tests of safety regarding how it’s processed, the products constituents, and exposure to consumers.

Crominex®3+ is a unique trivalent chromium supplement prepared by complexing trivalent chromium chloride with two natural products, Phyllanthus emblica (Capros®) and purified Shilajit (PrimaVie®) in order to minimize the conversion of chromium III to toxic chromium VI. Crominex®3+ is designed to give excellent content uniformity in finished dosage forms. Two recent studies, which are currently pending publication, have shown that Crominex®3+ is much more efficacious than all the other branded chromium products (chromium picolinate, chromium polynicotinate and chromium dinicocysteinate) in reducing HbA1c levels and in improving cardiac risk factors (endothelial function, lipid profile, biomarkers of oxidative stress). In addition, it showed highly significant synergistic activity, compared to the activity of the individual components. Another published clinical study with Crominex® 3+ in adjuvant therapy with prescription oral anti-diabetic drugs in type 2 diabetics has shown that it can reduce blood glucose levels, especially post-prandial. Crominex®3+ has also been proven efficacious in pet health. Two published studies – one in arthritic dogs and the other in arthritic horses – at Murray State University in Kentucky, have shown that Crominex® 3+ has significantly reduced arthritic pain in dogs as well as horses. Crominex®3+ would be ideal as a standalone product for blood glucose support and heart health support. It can also be added to an existing heart health formula, such as a omega 3 or CoQ10, in order to have broader heart health coverage. Due to its extremely low cost (each 400 mcg dose costs ¢ 0.75), it can be added to a formula with a very minimal increase in cost. Crominex®3+ is a safe and efficacious product that does much more than JUST blood glucose support.

For more information on Crominex®3+ and Natreon’s other patented ingredients, please visit

About Natreon Inc.
Natreon Inc. is a 16 year old company located in New Jersey with a state of the art R&D facility in Kolkata, India, and is focused on developing and marketing Ayurvedic products backed by extensive research, high degree of standardization, multiple clinical studies, safety studies, and intellectual property. Natreon’s R&D team is headed by Prof. Shibnath Ghosal, a Fulbright scholar and an eminent natural product chemist with hundreds of publications in scientific journals and a group of Ph.D. and Master’s level scientists. Natreon’s scientific research includes process optimization, development of chromatographic analytical methods such as HPLC, HPTLC, GC-MS and LC-MS for standardization, development of marker compounds, and pharmacological studies. Safety studies are done in the USA and clinical studies are conducted in reputed institutes in India as well as the USA.
For more information on PrimaVie® and Natreon’s other patented ingredients, please visit