was able to demonstrate the function of Ubiquinol in gene expression: “People with low levels of Ubiquinol have higher levels of BNP and CRP, which are essential molecules of inflammatory processes and play an important role as risk factors for heart disease.” Ubiquinol is also vital for improving recovery in healthy individuals. The latest products target active “Best Agers” who want to stay healthy, as well as athletes who are keen to optimise their immune defences and muscular capabilities. Several European sports professionals have already started to use Kaneka Ubiquinol™, and its activity for athletes is backed by various scientific studies. Having thus far been mainly available in capsule form, Kaneka has now developed a stabilized Ubiquinol powder for use in powdered and liquid applications.
Furthermore, Kaneka will present the Novel Food-approved plant extract Glavonoid™, which was originally developed to prevent metabolic syndrome. Derived from licorice root (Glycyrrhiza glabra L.), Glavonoid™ has been proven to be completely safe and is approved by the European authorities with Novel Food ingredient status. An advanced, patented extraction process ensures that the ingredient does not contain any glycyrrhizinic acid, making it free from the unwanted side-effects of licorice. Glavonoid™ is able to increase the body’s own fat burning ability, while at the same time decreasing fat synthesis by down-regulating genes that are involved in fatty acid development. Since 2015, Glavonoid™ has been approved for extended use in foods for medical purposes and energy-restricted diets for weight reduction. A food supplement containing Glavonoid™ was now submitted for the Nutraingredients Award for best new weight management supplement of the year.
A recent randomized, double-blind, placebo-controlled study conducted in 2016 verified that Glavonoid™ can also increase skeletal muscle mass in humans in combination with exercise. During the study, male American Football athletes ingested 300 mg Glavonoid™ per day over 8 weeks of training. Ultrasound imaging analysis revealed that the muscle thickness of the anterior thighs and anterior brachial regions in the Glavonoid™ group were both significantly increased by 2.5% at week 8 in comparison to baseline. There was no such increase in the placebo group. Abdominal muscle thickness increased in both groups, but the increase was 1.8 times greater in the Glavonoid group than in the placebo group (p<0.05). It can therefore be seen that Glavonoid™ is ideal for inclusion in products aimed at the sports and fitness market.
 Fischer, A. et al.: Coenzyme Q10 redox state predicts the level of the c-reactive protein (CRP), a biomarker of inflammation, in a large European cohort. Biofactors 42(3):268-76.
 Myojin, C. et al.: Liquorice flavonoid oil increased skeletal muscle thickness as assessed by ultrasound in training football athletes. Nutrafoods 2016.